Laboratory diagnosis of antiphospholipid antibodies

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Laboratory Diagnosis of Antiphospholipid Antibodies

Antiphospholipid antibodies may be associated with venous thromboembolism and/or arterial thromboses or miscarriages; their heterogeneity complicates the laboratory diagnosis. For a long time, they were believed to be directed against anionic phospholipids. More recently, it has been demonstrated that these antibodies are directed at plasma proteins bound most of the time to a phos-pholipid sur...

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[Antiphospholipid antibodies and antiphospholipid syndrome: diagnosis and management].

Antiphospholipid syndrome is an acquired autoimmune thrombophilia that produces significant morbidity and mortality. Its diagnosis requires the presence of antiphospholipid antibodies and clinical manifestations that include thrombotic phenomena and/or recurrent miscarriages. Antiphospholipid antibodies may be detected in many instances, including healthy subjects. Clinical manifestations are v...

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Antiphospholipid antibodies.

Antiphospholipid antibodies (APLAs) are proteins that may be present in the blood and may increase your risk for blood clots or pregnancy losses. If you have a history of blood clots or recurrent pregnancy losses, you may have been tested for the presence of APLAs in your blood. The purpose of this Cardiology Patient Page is to provide information for persons with APLAs about the disorder and a...

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Clinical and laboratory findings in patients with antiphospholipid antibodies and cerebral ischemia. The Antiphospholipid Antibodies in Stroke Study Group.

We reviewed the clinical and laboratory data of 128 patients with cerebrovascular disease and antiphospholipid antibodies. Cases were evenly divided between men and women, and the mean age of the study group was 46 years. Cerebral infarction occurred in 97 patients, and transient hemispheric ischemic attacks without stroke were recorded in 19; 12 suffered ocular ischemia. Systemic lupus erythem...

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Prevalence of Antiphospholipid Antibodies in Syrian Patients with Thrombosis

Background: Antiphospholipid antibodies (aPL) are a heterogeneous family of anti-bodies associated with thrombosis and other complications. Objective: To study the prevalence of aPL in patients with thrombosis at Aleppo University Hospitals, Syria. Methods: One hundred and fifty-seven patients with venous and arterial thrombosis and 63 healthy controls were studied. Anticardiolipin antibodies (...

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ژورنال

عنوان ژورنال: Infectious Diseases in Obstetrics and Gynecology

سال: 1997

ISSN: 1064-7449,1098-0997

DOI: 10.1002/(sici)1098-0997(1997)5:2<181::aid-idog14>3.0.co;2-k